The 3rd Biennial Ghana Women Entrepreneurship Summit (GWES 2022) was a crucible of intellect, poise, commitment, and challenge in ways we never anticipated. Right from the opening at Kempinksi Hotel in Accra on April 25, one could sense the passion from attendees. People were very enthusiastic to learn from a carefully curated cast of speakers, panelists, and facilitators, the intricacies of running a business in Ghana with a specific focus on the issues that hinder or present opportunities for women.